Retinal aging in the diurnal Chilean rodent (Octodon degus): histological, ultrastructural and neurochemical alterations of the vertical information processing pathway
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چکیده
منابع مشابه
Retinal aging in the diurnal Chilean rodent (Octodon degus): histological, ultrastructural and neurochemical alterations of the vertical information processing pathway
The retina is sensitive to age-dependent degeneration. To find suitable animal models to understand and map this process has particular importance. The degu (Octodon degus) is a diurnal rodent with dichromatic color vision. Its retinal structure is similar to that in humans in many respects, therefore, it is well suited to study retinal aging. Histological, cell type-specific and ultrastructura...
متن کاملOctodon degus: a diurnal, social, and long-lived rodent.
Octodon degus is a moderate-sized, precocious, but slowly maturing, hystricomorph rodent from central Chile. We have used this species to study a variety of questions about circadian rhythms in a diurnal mammal that readily adapts to most laboratory settings. In collaboration with others, we have found that a number of fundamental features of circadian function differ in this diurnal rodent com...
متن کاملRetinal projection to the dorsal raphe nucleus in the Chilean degus (Octodon degus).
A substantial projection from the retina to the dorsal raphe nucleus (DRN) has been demonstrated in the Chilean degus, a diurnal/crepuscular hystricomorph rodent. Following intraocular injection of cholera toxin subunit B (CTB), immunocytochemically labeled CTB-positive axons and terminals were observed in all major retinorecipient nuclei as well as in the DRN and periaqueductal gray (PAG) of t...
متن کاملOdor-specific effects on reentrainment following phase advances in the diurnal rodent, Octodon degus.
Reentrainment following phase shifts of the light-dark (LD) cycle is accelerated in Octodon degus in the presence of olfactory social cues (i.e., odors) produced by conspecifics. However, not all odors from conspecifics were effective in facilitating reentrainment after a phase advance. In the current experiments, we examined whether nonanimal odors, odors from another species, or conspecific o...
متن کاملEstrus- and steroid-induced changes in circadian rhythms in a diurnal rodent, Octodon degus.
Diurnal Octodon degus exhibited marked alterations in activity and temperature in conjunction with the 3 wk estrous cycle when housed in LD12:12 light cycle. On the day of estrus, mean daily activity increases 109%, mean core temperature rises .4 degree C, activity onset is advanced 2 h, and amplitudes of both rhythms decline compared with the 3 days prior to estrus. On the day following estrus...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2015
ISSN: 1662-5102
DOI: 10.3389/fncel.2015.00126